Influence of percutaneous abscess drainage on severe postoperative septic complications in patients with Crohn's disease

Mueller-Wille, Rene and Iesalnieks, Igors and Dornia, Christian and Ott, Claudia and Jung, Ernst Michael and Friedrich, Chris and Schill, Gabriela and Hoffstetter, Patrick and Zorger, Niels and Schreyer, Andreas G. (2011) Influence of percutaneous abscess drainage on severe postoperative septic complications in patients with Crohn's disease. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 26 (6). pp. 769-774. ISSN 0179-1958,

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Abstract

Purpose Severe postoperative intra-abdominal septic complications (IASC) such as an anastomotic leak, intra-abdominal abscess, and fistula are significantly associated with the presence of spontaneous intra-abdominal abscess at the time of laparotomy in patients with Crohn's disease (CD). The purpose of this study was to compare the incidence of severe postoperative IASC in patients undergoing intestinal resections with and without preoperative percutaneous abscess drainage (PAD) before definitive surgery. Methods Using a prospective surgical database, we searched for patients with CD and spontaneous intra-abdominal abscesses who underwent intestinal resection at our hospital from May 2005 to February 2009. Postoperative IASC were defined as anastomotic leaks, abscess, and fistula within 1 month after surgery. We compared the incidence of postoperative IASC in patients with (group I) and without (group II) preoperative PAD (Fisher's exact test). Results We identified 25 patients (15 men, 10 women; mean age, 31 years) with spontaneous intra-abdominal abscesses. PAD was performed in 12 of 25 patients (48%), with an average of 37 days before surgery (range, 6-83 days). The overall rate of postoperative IASC was 48% (12 of 25 patients). In group I, postoperative IASC occurred in 3 of 12 patients (25%). In group II, postoperative IASC were assessed in 9 of 13 patients (69%). The differences between these two groups were considered to be statistically significant (p = 0.04). Conclusion PAD of intra-abdominal abscesses before surgery could significantly reduce the occurrence of severe postoperative IASC in patients with CD.

Item Type: Article
Uncontrolled Keywords: RISK-FACTORS; PREOPERATIVE MANAGEMENT; INTRAABDOMINAL ABSCESS; CONSECUTIVE PATIENTS; RECURRENCE; SURGERY; Abscess; Drainage; Crohn's disease; Complications
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Medicine > Lehrstuhl für Innere Medizin I
Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 15 Jun 2020 09:55
Last Modified: 15 Jun 2020 09:55
URI: https://pred.uni-regensburg.de/id/eprint/20746

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