4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene as a Bright Fluorescent Label for DNA

Ehrenschwender, Thomas and Wagenknecht, Hans-Achim (2011) 4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene as a Bright Fluorescent Label for DNA. JOURNAL OF ORGANIC CHEMISTRY, 76 (7). pp. 2301-2304. ISSN 0022-3263,

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Abstract

4,4-Difluono-4-bora-3a,4a-diaza-s-indacene (BODIPY) as a fluorescent label can be incorporated into DNA by two conceptually different ways: the non-nucleosidic DNA base surrogate Bo exhibits high brightness but no preferential basepairing properties, whereas the BODIPY-mofidined uridine BodU has reduced quantum yields but shows preferred Watson-Crick base pairing with adenine.

Item Type: Article
Uncontrolled Keywords: BODIPY DYES; SPECTROSCOPIC PROPERTIES; REVERSIBLE TERMINATOR; HIGHLY FLUORESCENT; PROBES; BASE; DERIVATIVES; NUCLEOTIDE; DESIGN; PROTEINS;
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Alumni or Retired Professors > Arbeitskreis Prof. Dr. Hans-Achim Wagenknecht
Depositing User: Dr. Gernot Deinzer
Date Deposited: 23 Jun 2020 06:57
Last Modified: 23 Jun 2020 06:57
URI: https://pred.uni-regensburg.de/id/eprint/21057

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