Glockzin, Gabriel and Renner, Philipp and Popp, Felix C. and Dahlke, Marc H. and von Breitenbuch, Philipp and Schlitt, Hans J. and Piso, Pompiliu (2011) Hepatobiliary Procedures in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy. ANNALS OF SURGICAL ONCOLOGY, 18 (4). pp. 1052-1059. ISSN 1068-9265,
Full text not available from this repository. (Request a copy)Abstract
The long-term prognosis of patients with peritoneal malignancies has greatly improved since the introduction of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Nevertheless, CRS can be associated with high postoperative morbidity. In this retrospective study, we analyzed the influence of hepatobiliary surgery as part of CRS on postoperative short-term patient outcome. Between 2005 and 2008, a total of 63 (25%) of 252 patients with peritoneal surface malignancies undergoing CRS and HIPEC required hepatobiliary surgery. Liver resection was performed in 22, resection of Glisson capsule in 39, and bile duct resection in 2 patients. The mean age of the study population was 49.3 years. Thirty-four patients (54%) were women. Complete macroscopic cytoreduction (CC-0/1) was reached in 59 patients (93.7%). The median hospital stay was 18 days. Twenty-two patients developed minor complications (35%), such as moderate fever, pain, or secondary wound healing. In 21 patients (33%), severe complications occurred, most commonly pancreatitis and abdominal abscess. Three patients (4.8%) developed a biliary leakage. Of these, 2 had to be reoperated. In our experience, hepatobiliary procedures have to be performed in up to one-third of patients and are associated with a low rate of specific complications, such as biliary leakages.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PERITONEAL SURFACE MALIGNANCY; COLORECTAL-CANCER; SYSTEMIC CHEMOTHERAPY; MORTALITY ANALYSIS; RANDOMIZED-TRIAL; LEARNING-CURVE; CARCINOMATOSIS; MORBIDITY; CHEMOHYPERTHERMIA; EXPERIENCE; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 23 Jun 2020 09:00 |
| Last Modified: | 23 Jun 2020 09:00 |
| URI: | https://pred.uni-regensburg.de/id/eprint/21084 |
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