A Copper(I) Isonitrile Complex as a Heterogeneous Catalyst for Azide-Alkyne Cycloaddition in Water

Liu, Meina and Reiser, Oliver (2011) A Copper(I) Isonitrile Complex as a Heterogeneous Catalyst for Azide-Alkyne Cycloaddition in Water. ORGANIC LETTERS, 13 (5). pp. 1102-1105. ISSN 1523-7060,

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Abstract

A structurally well-defined copper(I) isonitrile complex is shown to be an efficient, heterogeneous catalyst for the Huisgen azide-alkyne 1,3-dipolar cycloaddition under mild conditions in water. Notably, this catalyst can also be utilized in a three-component reaction of halides, sodium azide and alkynes to form 1,4-disubstituted 1,2,3-triazoles in high yields. Furthermore, it can be readily recovered by precipitation and filtration and recycled for at least five runs without significant loss of activity.

Item Type: Article
Uncontrolled Keywords: CARBON DOUBLE-BONDS; CLICK CHEMISTRY; 1,3-DIPOLAR CYCLOADDITIONS; AZABIS(OXAZOLINE) LIGANDS; HUISGEN CYCLOADDITION; TERMINAL ALKYNES; BIS-SILYLATION; ISOCYANIDE; TRIAZOLE; POLYMER;
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
Depositing User: Dr. Gernot Deinzer
Date Deposited: 24 Jun 2020 05:56
Last Modified: 24 Jun 2020 05:56
URI: https://pred.uni-regensburg.de/id/eprint/21123

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