Impact of the Eurotransplant High-Urgency Heart Allocation System on the Outcome of Transplant Candidates in Germany

Haneya, A. and Haake, N. and Diez, C. and Puehler, T. and Cremer, J. and Schmid, C. and Hirt, S. W. (2011) Impact of the Eurotransplant High-Urgency Heart Allocation System on the Outcome of Transplant Candidates in Germany. THORACIC AND CARDIOVASCULAR SURGEON, 59 (2). pp. 93-98. ISSN 0171-6425,

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Abstract

Background: In 2000, the Eurotransplant Foundation changed the allocation criteria following the enactment of the German Transplantation Law (GTL). Our study investigated the impact of the new allocation system on outcomes after heart transplantation (HTx) in Germany. Methods: We compared 2 cohorts of patients who underwent HTx at our institution in two different 3-year periods before (Group 1: 01/1995-12/1997) and after (Group 2: 01/2003-12/2005) implementation of the new system. Results: An increase in the ratio of HTx performed on an urgency basis was found in Group 2 (8.3% vs. 87.2%; p < 0.001). The median waiting time and the ischemia time were significantly lower in Group 1 (p < 0.05). Postoperatively, the length of ICU stay was significantly higher in Group 2 (p = 0.04). Conclusion: The new allocation system decreased the proportion of local and regional organ harvesting. It generates a higher ischemia time without increasing the number of transplantations and without improving the clinical outcome after HTx. The severity of heart failure, rate of secondary organ impairment, and comorbidity is markedly elevated in patients waiting for HTx on HU.

Item Type: Article
Uncontrolled Keywords: INTERNATIONAL-SOCIETY; LUNG-TRANSPLANTATION; ISCHEMIA; REGISTRY; PROGRAM; COSTS; DONOR; heart and lung transplantation; cardiomyopathy; heart disease; heart transplantation; HU allocation; Eurotransplant Foundation
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 24 Jun 2020 14:45
Last Modified: 24 Jun 2020 14:45
URI: https://pred.uni-regensburg.de/id/eprint/21198

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