Timmer, Antje and Behrens, Rolf and Buderus, Stephan and Findeisen, Annette and Hauer, Almuthe and Keller, Klaus-Michael and Kliemann, Guido and Lang, Thomas and Lohr, Wolfgang and Rzehak, Peter and Koletzko, Sibylle (2011) Childhood Onset Inflammatory Bowel Disease: Predictors of Delayed Diagnosis from the CEDATA German-Language Pediatric Inflammatory Bowel Disease Registry. JOURNAL OF PEDIATRICS, 158 (3). 467-U151. ISSN 0022-3476, 1097-6833
Full text not available from this repository. (Request a copy)Abstract
Objectives To examine predictors of delayed diagnosis of inflammatory bowel disease in children and adolescents. Study design A total of 2436 patients (age 0-18 years) with Crohn's disease, ulcerative colitis, or unclassified colitis were included from 53 pediatric gastroenterologists. Predictors were examined with the proportional hazards model, presented as hazard ratios (HR) with 95% confidence intervals. HR < 1.0 represent factors associated with late diagnosis. Results Median time to diagnosis was 4 (2-8) months. Crohn's disease (HR 0.62; 0.56-0.68), and within Crohn's disease, ileal disease (HR 0.77, 95% confidence interval 0.67 to 0.89) were associated with delayed diagnosis. Chances for early diagnosis increased with increasing age (HR 1.07 per year of age; 1.06 to 1.08). There was also an effect by center (HR 0.63, 0.52 to 0.67), but not by sex or country (Austria vs Germany). Growth failure was more common in those cases with delayed diagnosis. Conclusions There is still concern about delays in the diagnosis of inflammatory bowel disease in the very young and in children with small bowel disease. Inequalities of care by region require further investigation. (J Pediatr 2011;158:467-73).
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CROHNS-DISEASE; NATURAL-HISTORY; GROWTH FAILURE; POPULATION; CHILDREN; ISSUES; INTERVENTIONS; HYPERTENSION; DISPARITIES; PREVALENCE; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Kinder- und Jugendmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 25 Jun 2020 12:05 |
| Last Modified: | 25 Jun 2020 12:05 |
| URI: | https://pred.uni-regensburg.de/id/eprint/21213 |
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