Monomer-on-Monomer (MoM) Mitsunobu Reaction: Facile Purification Utilizing Surface-Initiated Sequestration

Maity, Pradip K. and Rolfe, Alan and Samarakoon, Thiwanka B. and Faisal, Saqib and Kurtz, Ryan D. and Long, Toby R. and Schaetz, Alexander and Flynn, Daniel L. and Grass, Robert N. and Stark, Wendelin J. and Reiser, Oliver and Hanson, Paul R. (2011) Monomer-on-Monomer (MoM) Mitsunobu Reaction: Facile Purification Utilizing Surface-Initiated Sequestration. ORGANIC LETTERS, 13 (1). pp. 8-10. ISSN 1523-7060,

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Abstract

A monomer-on-monomer (MoM) Mitsunobu reaction utilizing norbornenyl-tagged (Nb-tagged) reagents is reported, whereby purification was rapidly achieved by employing ring-opening metathesis polymerization, which was initiated by any of three methods utilizing Grubbs catalyst: (i) free catalyst in solution, (ii) surface-initiated catalyst-armed silica, or (iii) surface-initiated catalyst-armed Co/C magnetic nanoparticles.

Item Type: Article
Uncontrolled Keywords: OPENING METATHESIS POLYMERIZATION; CHEMICAL LIBRARY SYNTHESIS; PARALLEL SYNTHESIS; ROM POLYMERIZATION; HIGH-LOAD; CATALYSTS; REAGENTS; NANOPARTICLES; RUCL2(=CHR)(PR(3))(2); DERIVATIVES;
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
Depositing User: Dr. Gernot Deinzer
Date Deposited: 29 Jun 2020 05:22
Last Modified: 29 Jun 2020 05:22
URI: https://pred.uni-regensburg.de/id/eprint/21401

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