Intramolecular monomer-on-monomer (MoM) Mitsunobu cyclization for the synthesis of benzofused thiadiazepine-dioxides

Maity, Pradip K. and Kainz, Quirin M. and Faisal, Saqib and Rolfe, Alan and Samarakoon, Thiwanka. B. and Basha, Fatima Z. and Reiser, Oliver and Hanson, Paul R. (2011) Intramolecular monomer-on-monomer (MoM) Mitsunobu cyclization for the synthesis of benzofused thiadiazepine-dioxides. CHEMICAL COMMUNICATIONS, 47 (46). pp. 12524-12526. ISSN 1359-7345,

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Abstract

The utilization of a monomer-on-monomer (MoM) intramolecular Mitsunobu cyclization reaction employing norbornenyl-tagged (Nb-tagged) reagents is reported for the synthesis of benzofused thiadiazepine-dioxides. Facile purification was achieved via ring-opening metathesis (ROM) polymerization initiated by one of three metathesis catalyst methods: (i) free metathesis catalyst, (ii) surface-initiated catalyst-armed silica, or (iii) surface-initiated catalyst-armed Co/C magnetic nanoparticles.

Item Type: Article
Uncontrolled Keywords: OPENING METATHESIS POLYMERIZATION; HETEROCYCLIC SCAFFOLDS; PALLADIUM CATALYST; LIBRARY SYNTHESIS; REAGENTS; RUCL2(=CHR)(PR(3))(2); AZODICARBOXYLATE; NANOPARTICLES; GENERATION; SEPARATION;
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
Depositing User: Dr. Gernot Deinzer
Date Deposited: 29 Jun 2020 09:08
Last Modified: 29 Jun 2020 09:08
URI: https://pred.uni-regensburg.de/id/eprint/21515

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