Wieneke, Ralph and Bernecker, Anja and Riedel, Radostan and Sumper, Manfred and Steinem, Claudia and Geyer, Armin (2011) Silica precipitation with synthetic silaffin peptides. ORGANIC & BIOMOLECULAR CHEMISTRY, 9 (15). pp. 5482-5486. ISSN 1477-0520,
Full text not available from this repository. (Request a copy)Abstract
Silaffins are highly charged proteins which are one of the major contributing compounds that are thought to be responsible for the formation of the hierarchically structured silica-based cell walls of diatoms. Here we describe the synthesis of an oligo-propyleneamine substituted lysine derivative and its incorporation into the KXXK peptide motif occurring repeatedly in silaffins. N(epsilon)-alkylation of lysine was achieved by a Mitsunobu reaction to obtain a protected lysine derivative which is convenient for solid phase peptide synthesis. Quantitative silica precipitation experiments together with structural information about the precipitated silica structures gained by scanning electron microscopy revealed a dependence of the amount and form of the silica precipitates on the peptide structure.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DIATOM THALASSIOSIRA-PSEUDONANA; MORPHOGENESIS; POLYAMINES; MORPHOLOGY; BIOSILICA; |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Alumni or Retired > Prof. Dr. Manfred Sumper |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 01 Jul 2020 10:26 |
| Last Modified: | 01 Jul 2020 10:26 |
| URI: | https://pred.uni-regensburg.de/id/eprint/21646 |
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