Veitt, R. and Reichardt, M. and Wenzel, J. and Jilg, W. (2011) Autochthonous Hepatitis E-Virus Infection as Cause of Acute Hepatitis in Germany - a Case Report. ZEITSCHRIFT FUR GASTROENTEROLOGIE, 49 (1). pp. 42-46. ISSN 0044-2771,
Full text not available from this repository. (Request a copy)Abstract
There is an increasing body of evidence that hepatitis E virus (HEV) triggers acute hepatitis not only in tropical and subtropical regions of Asia, Africa, and America with low sanitary standards but also in highly industrialized countries. We here report on two patients from Thuringia (Germany) with a HEV infection without a recent stay abroad. All other common causes of hepatitis were excluded. Transaminases were significantly incresed in both cases, while icterus could be proven in one patient, only. Both patients fully recovered in the long-term course. Epidemiological and phylogenetic data from viral analyses suggest that HEV infection has to be considered as a zoonosis. It is likely that viral transmission from animals to humans occurs through insufficiently cooked meat or entrails, e.g., from pigs or wild animals. In summary, HEV infection is a relevant differential diagnosis in acute non-A/B/C viral hepatitis. Further studies are required for the identification of other transmission pathways, pathogen reservoirs as well as novel concepts for prophylaxis, especially for patients at risk for hepatic diseases.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CHRONIC LIVER-DISEASE; LOCAL GROCERY STORES; VIRAL-HEPATITIS; BLOOD-DONORS; WILD BOAR; E VACCINE; TRANSMISSION; SWINE; RISK; DEER; hepatitis E; Germany; autochthonous hepatitis; acute hepatitis |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 02 Jul 2020 12:57 |
| Last Modified: | 02 Jul 2020 12:57 |
| URI: | https://pred.uni-regensburg.de/id/eprint/21711 |
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