Markl, Peter and Prantl, Lukas and Schreml, Stephan and Babilas, Philipp and Landthaler, Michael and Schwarze, Hardy (2010) Management of Split-Thickness Donor Sites With Synthetic Wound Dressings Results of a Comparative Clinical Study. ANNALS OF PLASTIC SURGERY, 65 (5). pp. 490-496. ISSN 0148-7043, 1536-3708
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This prospective, randomized, single-blinded, clinical study aimed at evaluating 3 different synthetic wound dressings for treating split-thickness skin graft donor sites. Seventy-seven patients were randomly assigned to 3 study groups: Suprathel, Biatain-Ibu, Mepitel. Wounds were inspected daily until complete reepithelization. Ease of care, treatment costs, and scar development after a 6 months follow-up were evaluated. Suprathel showed significant (P <= 0.001) pain reduction after 24 hours but increasing pain scores on the 5th day of treatment. Biatain-Ibu showed significant pain relief immediately after application and during the entire treatment period (P < 0.05). Mepitel did not show any significant pain reduction. No differences were seen with regard to healing time, quality of reepithelization, and scar development. Biatain-Ibu had the lowest overall treatment costs (P <= 0.001). The investigated materials did not differ with regard to quality and acceleration of the healing process, but Biatain-Ibu seems to be the most appropriate dressing material in terms of cost-effectiveness.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | EPITHELIAL SUBSTITUTE SUPRATHEL(R); THERMALLY INJURED HANDS; VENOUS LEG ULCERS; SKIN SUBSTITUTE; PAIN; STRATEGIES; EFFICACY; CHILDREN; MEPITEL; Suprathel; Biatain; Mepitel; wound healing; pain; split-thickness skin graft; donor site |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 06 Jul 2020 13:22 |
| Last Modified: | 06 Jul 2020 13:22 |
| URI: | https://pred.uni-regensburg.de/id/eprint/23912 |
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