Amyloid in skin and brain: What's the link?

Schreml, Stephan and Kaiser, Elmar and Landthaler, Michael and Szeimies, Rolf-Markus and Babilas, Philipp (2010) Amyloid in skin and brain: What's the link? EXPERIMENTAL DERMATOLOGY, 19 (11). pp. 953-957. ISSN 0906-6705, 1600-0625

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Abstract

For too long, amyloids have been under general suspicion to merely cause diseases. In recent years, we have learned that these interesting proteins may also fulfill important biological tasks. Moreover, recent publications show emerging evidence for a so-called brain-skin axis. This viewpoint paper aims to address the question what is known about the link between brain and skin based on the literature available for two diseases caused by amyloid formation: Alzheimer's disease (AD) and cutaneous amyloidoses. In addition, we acquaint the reader with a different perspective on the role of amyloid in skin and brain.

Item Type: Article
Uncontrolled Keywords: MILD COGNITIVE IMPAIRMENT; NERVE GROWTH-FACTOR; ALZHEIMERS-DISEASE; NEUROGENIC INFLAMMATION; SEQUENCE DETERMINANTS; FIBRIL FORMATION; P-COMPONENT; PROTEIN AGGREGATION; BETA-PROTEIN; TAU-PROTEIN; Alzheimer's disease; amyloid; amyloidoses; brain-skin axis; functional
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 07 Jul 2020 07:02
Last Modified: 07 Jul 2020 07:02
URI: https://pred.uni-regensburg.de/id/eprint/23933

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