Wound healing in the 21st century

Schreml, Stephan and Szeimies, Rolf-Markus and Prantl, Lukas and Landthaler, Michael and Babilas, Philipp (2010) Wound healing in the 21st century. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 63 (5). pp. 866-881. ISSN 0190-9622,

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Abstract

Delayed wound healing is one of the major therapeutic and economic issues in medicine today. Cutaneous wound healing is an extremely well-regulated and complex process basically divided into 3 phases: inflammation, proliferation, and tissue remodeling. Unfortunately, we still do not understand this process precisely enough to give direction effectively to impaired healing processes. There have been many new developments in wound healing that provide fascinating insights and may improve our ability to manage clinical problems. Our goal is to acquaint the reader with selected major novel findings about cutaneous wound healing that have been published since the beginning of the new millennium. We discuss advances in areas such as genetics, proteases, cytokines, chemokines, and regulatory peptides, as well as therapeutic strategies, all set in the framework of the different phases of wound healing. (J Am Acad Dermatol 2010;63:866-81.)

Item Type: Article
Uncontrolled Keywords: ANTIMICROBIAL PEPTIDE LL-37; FIBROBLAST-GROWTH-FACTOR; HUMAN DERMAL FIBROBLASTS; NF-KAPPA-B; KERATINOCYTE MIGRATION; EPIDERMAL-GROWTH; SKIN WOUNDS; IN-VITRO; SIGNALING PATHWAYS; CATHELICIDIN LL-37; cellular; molecular; novel findings; signal transduction; pH value; skin wound
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 07 Jul 2020 09:59
Last Modified: 07 Jul 2020 09:59
URI: https://pred.uni-regensburg.de/id/eprint/23961

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