Brittan-Powell, Elizabeth E. and Dooling, Robert J. and Ryals, Brenda and Gleich, Otto (2010) Electrophysiological and morphological development of the inner ear in Belgian Waters lager canaries. HEARING RESEARCH, 269 (1-2). pp. 56-69. ISSN 0378-5955, 1878-5891
Full text not available from this repository. (Request a copy)Abstract
Belgian Waterslager (BW) canaries have an inherited hearing loss due to missing and abnormal hair cells, but it is unclear whether the loss is congenital or developmental. We used auditory brainstem responses and scanning electron microscopy to describe the development of auditory sensitivity and hair cell abnormalities in BW and non-BW canaries. In both strains, adult ABR thresholds were higher than behavioral thresholds, but BW canaries exhibited higher thresholds than non-BW canaries across all frequencies. Immediately post-hatch, ABR thresholds and hair cell numbers were similar in both strains. Two weeks later, thresholds were significantly higher in BW canaries, and hair cell number progressively decreased as the birds aged. These data show that in BW canaries: the peripheral auditory system is functionally similar to non-BW canary from hatch to 2 weeks, ABR thresholds improve during this developmental period, actually becoming better than those of adults, but then worsen as the bird continues to age. Hair cell number and appearance is similar to non-BW canaries at hatch but progressively declines after 30 days of age. These data show that the hearing loss characteristic of BW canaries is, at least in part, developmental and is established by the time song learning begins. (C) 2010 Elsevier B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | AUDITORY-BRAIN-STEM; GERBIL MERIONES-UNGUICULATUS; HAIR CELL REGENERATION; BUDGERIGARS MELOPSITTACUS-UNDULATUS; ANTEROVENTRAL COCHLEAR NUCLEUS; SENSORINEURAL HEARING-LOSS; AGE-RELATED-CHANGES; SERINUS-CANARIUS; EVOKED POTENTIALS; MONGOLIAN GERBIL; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 13 Jul 2020 05:25 |
| Last Modified: | 13 Jul 2020 05:27 |
| URI: | https://pred.uni-regensburg.de/id/eprint/24072 |
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