Ried, M. and Unger, P. and Puehler, T. and Haneya, A. and Schmid, C. and Diez, C. (2010) Mild-to-Moderate COPD as a Risk Factor for Increased 30-Day Mortality in Cardiac Surgery. THORACIC AND CARDIOVASCULAR SURGEON, 58 (7). pp. 387-391. ISSN 0171-6425,
Full text not available from this repository. (Request a copy)Abstract
Background: Chronic obstructive pulmonary disease (COPD) is still a serious comorbidity in surgical procedures. We assessed the impact of mild to moderate COPD in a modern cardiac surgery unit. Methods: An age-, gender- and operation-matched cohort analysis of 242 patients treated between 01/2006 and 12/2008 was performed. COPD was defined as a FEV1 < 80% and a FEV1/FVC ratio < 0.7 in preoperative spirometry. Primary end point was 30-day mortality. Results: Preoperative beta-agonist treatment of COPD patients was noted for 43% of patients and not in the control group. After comparable surgery, postoperative respiratory failure was more frequent in COPD patients (10.4% vs. 2.5%, p = 0.02), whereas median ventilation time (12 h) and rate of reintubation (2.5% vs. 3.5%) did not significantly differ between both groups. Intensive care and hospital stay were significantly longer in the COPD group (p= 0.02 and p = 0.04), and 30-day mortality was significantly higher in COPD patients (0.8% vs. 6.1%, p = 0.03). Conclusions: COPD increases 30-day mortality, postoperative pulmonary complications, ICU stay and hospital stay. Proper identification and therapy may help to improve outcome in this high-risk population.
Item Type: | Article |
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Uncontrolled Keywords: | OBSTRUCTIVE PULMONARY-DISEASE; CORONARY-BYPASS; PREDICTION; SEVERITY; SURVIVAL; FAILURE; cardiovascular surgery; COPD; perioperative mortality; morbidity |
Subjects: | 600 Technology > 610 Medical sciences Medicine |
Divisions: | Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie |
Depositing User: | Dr. Gernot Deinzer |
Date Deposited: | 09 Jul 2020 13:29 |
Last Modified: | 09 Jul 2020 13:29 |
URI: | https://pred.uni-regensburg.de/id/eprint/24147 |
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