Nunez, Julio and Sanchis, Juan and Nunez, Eduardo and Bodi, Vicent and Mainar, Luis and Minana, Gema and Merlos, Pilar and Palau, Patricia and Husser, Oliver and Rumiz, Eva and Chorro, Francisco J. and Llacer, Angel (2010) Effect of Acute Heart Failure Following Discharge in Patients With Non-ST-Elevation Acute Coronary Syndrome on the Subsequent Risk of Death or Acute Myocardial Infarction. REVISTA ESPANOLA DE CARDIOLOGIA, 63 (9). pp. 1035-1044. ISSN 0300-8932,
Full text not available from this repository. (Request a copy)Abstract
Introduction and objectives. Little is known about how prognosis is influenced by readmission for acute heart failure (AHF) following non-ST-segment elevation acute coronary syndrome (NSTEACS). The aim of this study was to determine the prognostic effect of a first admission for AHF on the risk of acute myocardial infarction (AMI) or death in patients who survived an episode of high-risk NSTEACS. Methods. The study involved 972 consecutive patients with high-risk NSTEACS who survived after hospital admission. Readmission for AHF was selected as the main exposure variable, and its association with subsequent AMI or all-cause death was assessed using Cox proportional hazards models for time-dependent covariates that also included adjustment for competing risks. Results. After a median follow-up period of 30 [interquartile range, 12-48] months, 82 patients (8.4%) were admitted for AHF, 146 (15%) had an AMI, and 202 (20.8%) died. The median time to readmission for AHF was 203 [56-336] days after NSTEACS. Patients readmitted for AHF had an increased risk of subsequent death (hazard ratio [HR]=1.67; 95% confidence interval [CI], 1.13-2.45; P=.009) or AMI (HR=2.15; 95% CI, 1.41-3.27; P<.001), which was independent of baseline prognostic and timedependent variables. Conclusions. Readmission for AHF after high-risk NSTEACS was associated with an increased risk of subsequent death or AMI.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LEFT-VENTRICULAR DYSFUNCTION; SEGMENT ELEVATION; ARTERY-DISEASE; STABLE SURVIVORS; EUROPEAN-SOCIETY; TASK-FORCE; MANAGEMENT; IMPACT; REVASCULARIZATION; REGISTRY; Non-ST-segment acute coronary syndrome; Acute heart failure; Mortality; Myocardial infarction |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 15 Jul 2020 08:40 |
| Last Modified: | 15 Jul 2020 08:40 |
| URI: | https://pred.uni-regensburg.de/id/eprint/24298 |
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