Malinsky, Jan and Opekarova, Miroslava and Tanner, Widmar (2010) The lateral compartmentation of the yeast plasma membrane. YEAST, 27 (8spec). pp. 473-478. ISSN 0749-503X
Full text not available from this repository. (Request a copy)Abstract
The plasma membrane of Saccharomyces cerevisiae contains large microdomains enriched in ergosterol, which house at least nine integral proteins, including proton symporters. The domains adopt a characteristic structure of furrow-like invaginations typically seen in freeze-fracture pictures of fungal cells. Being stable for the time comparable with the cell cycle duration, they might be considered as fixed islands (rafts) in an otherwise fluid yeast plasma membrane. Rapidly moving endocytic marker proteins avoid the microdomains; the domain-accumulated proton symporters consequently show a reduced rate of substrate-induced endocytosis and turnover. Copyright (C) 2010 John Wiley & Sons, Ltd.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LIPID RAFTS; SACCHAROMYCES-CEREVISIAE; CELL-MEMBRANES; PROTEINS; DOMAINS; TRANSPORT; PERMEASE; SPHINGOLIPIDS; SEGREGATION; ENDOCYTOSIS; membrane microdomains; membrane structure; Can1; membrane compartment of Can1; protein turnover; confocal microscopy |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Pflanzenwissenschaften |
| Depositing User: | Petra Gürster |
| Date Deposited: | 16 Apr 2020 05:50 |
| Last Modified: | 16 Apr 2020 05:50 |
| URI: | https://pred.uni-regensburg.de/id/eprint/24440 |
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