Advancement of Mesenchymal Stem Cell Therapy in Solid Organ Transplantation (MISOT)

Hoogduijn, Martin J. and Popp, Felix C. and Grohnert, Anja and Crop, Meindert J. and van Rhijn, Marieke and Rowshani, Ajda T. and Eggenhofer, Elke and Renner, Philipp and Reinders, Marlies E. and Rabelink, Ton J. and van der Laan, Luc J. W. and Dor, Frank J. M. F. and IJzermans, Jan N. M. and Genever, Paul G. and Lange, Claudia and Durrbach, Antoine and Houtgraaf, Jaco H. and Christ, Bruno and Seifert, Martina and Shagidulin, Murat and Donckier, Vincent and Deans, Robert and Ringden, Olle and Perico, Norberto and Remuzzi, Giuseppe and Bartholomew, Amelia and Schlitt, Hans J. and Weimar, Willem and Baan, Carla C. and Dahlke, Marc H. (2010) Advancement of Mesenchymal Stem Cell Therapy in Solid Organ Transplantation (MISOT). TRANSPLANTATION, 90 (2). pp. 124-126. ISSN 0041-1337,

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Abstract

There is evolving interest in the use of mesenchymal stem cells (MSC) in solid organ transplantation. Pre-clinical transplantation models show efficacy of MSC in prolonging graft survival and a number of clinical studies are planned or underway. At a recent meeting of the MISOT consortium (MSC In Solid Organ Transplantation) the advances of these studies were evaluated and mechanisms underlying the potential effects of MSC discussed. Continued discussion is required for definition of safety and eventually efficacy endpoints for MSC therapy in solid organ transplantation.

Item Type: Article
Uncontrolled Keywords: VERSUS-HOST-DISEASE; IN-VITRO; SURVIVAL; REPAIR; VIVO; Mesenchymal stem cell; Solid organ transplantation; Clinical trial; MISOT
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 22 Jul 2020 06:29
Last Modified: 22 Jul 2020 06:29
URI: https://pred.uni-regensburg.de/id/eprint/24447

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