Schmidt-Wilcke, T. and Rosengarth, K. and Luerding, R. and Bogdahn, U. and Greenlee, M. W. (2010) Distinct patterns of functional and structural neuroplasticity associated with learning Morse code. NEUROIMAGE, 51 (3). pp. 1234-1241. ISSN 1053-8119,
Full text not available from this repository. (Request a copy)Abstract
Learning is based on neuroplasticity, i.e. on the capability of the brain to adapt to new experiences. Different mechanisms of neuroplasticity have been described, ranging from synaptic remodeling to changes in complex neural circuitry. To further study the relationship between changes in neural activity and changes in gray matter density associated with learning, we performed a combined longitudinal functional and morphometric magnetic resonance imaging (MRI) study on healthy volunteers who learned to decipher Morse code. We investigated 16 healthy subjects using functional MR imaging (fMRI) and voxel-based morphometry (VBM) before and after they had learned to decipher Morse code. The same set of Morse-code signals was presented to participants pre- and post-training. We found an increase in task-specific neural activity in brain regions known to be critically involved in language perception and memory, such as the inferior parietal cortex bilaterally and the medial parietal cortex during Morse code deciphering. Furthermore we found an increase in gray matter density in the left occipitotemporal region, extending into the fusiform gyms. Anatomically neighboring sites of functional and structural neuroplasticity were revealed in the left occipitotemporal/inferior temporal cortex, but these regions only marginally overlapped. Implications of this morpho-functional dissociation for learning concepts are discussed. (C) 2010 Elsevier Inc. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | EXERCISE INDUCES ANGIOGENESIS; VISUAL WORD RECOGNITION; BRAIN STRUCTURE CHANGES; SYNAPTIC PLASTICITY; CEREBRAL-CORTEX; WORKING-MEMORY; MOTOR CORTEX; FORM AREA; LANGUAGE; SPEECH; Learning; Brain plasticity; Brain morphology; Language processing; Longitudinal study |
| Subjects: | 100 Philosophy & psychology > 150 Psychology 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurologie Human Sciences > Institut für Psychologie > Lehrstuhl für Psychologie I (Allgemeine Psychologie I und Methodenlehre) - Prof. Dr. Mark W. Greenlee |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 27 Jul 2020 12:42 |
| Last Modified: | 27 Jul 2020 12:42 |
| URI: | https://pred.uni-regensburg.de/id/eprint/24527 |
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