Steinbauer, Julia M. and Schreml, Stephan and Kohl, Elisabeth A. and Karrer, Sigrid and Landthaler, Michael and Szeimies, Rolf-Markus (2010) Photodynamic therapy in dermatology. JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 8 (6). pp. 454-464. ISSN 1610-0379,
Full text not available from this repository. (Request a copy)Abstract
P>Photodynamic therapy (PDT) is a modern therapy modality, based upon the application of a photosensitizing agent like aminolevulinic acid, a physiological precursor of porphyrins, onto the tissue followed by illumination with light of the visible wavelength spectrum. During this oxygen-dependent reaction, reactive oxygen species (ROS) are generated that have immunomodulatory or cytotoxic effects. PDT shows excellent cosmetic results especially for its key indication in dermatology - the treatment of non-melanoma skin cancer. The associated pain and the low tissue penetration are the most frequent limiting factors of PDT. We review basic principles and recent developments in photosensitizers and light sources. Key oncological and non-oncological indications are presented as well.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 5-AMINOLEVULINIC ACID; METHYL AMINOLEVULINATE; PHASE-III; UPDATE; CANCER; photodynamic therapy; non-melanoma skin cancer; 5-aminolevulinic acid; non-oncological indications |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 29 Jul 2020 07:02 |
| Last Modified: | 29 Jul 2020 07:02 |
| URI: | https://pred.uni-regensburg.de/id/eprint/24624 |
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