Minimized Extracorporeal Circulation in Coronary Artery Bypass Surgery Is Equivalent to Standard Extracorporeal Circulation in Patients with Reduced Left Ventricular Function

Puehler, T. and Haneya, A. and Philipp, A. and Camboni, D. and Hirt, S. and Zink, W. and Lehle, K. and Rupprecht, L. and Kobuch, R. and Diez, C. and Schmid, C. (2010) Minimized Extracorporeal Circulation in Coronary Artery Bypass Surgery Is Equivalent to Standard Extracorporeal Circulation in Patients with Reduced Left Ventricular Function. THORACIC AND CARDIOVASCULAR SURGEON, 58 (4). pp. 204-209. ISSN 0171-6425, 1439-1902

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Abstract

Background: Minimized extracorporeal circulation (MECC) is a promising alternative to standard extracorporeal circulation (ECC) and its use is increasing in routine coronary bypass surgery. We analyzed the clinical outcome of patients with reduced left ventricular function who underwent coronary artery bypass surgery with MECC or with standard ECC. Methods: From January 2003 to September 2008, 238 patients with a left ventricular function < 30% underwent bypass surgery with ECC or MECC. The primary end point of our retrospective observational study was 30-day mortality. Secondary endpoints were the transfusion requirements, as well as intensive care and the in-hospital course. Results: Demographic data, comorbidities and left ventricular function were similar in the study groups. MECC patients had a tendency towards a lower 30-day mortality rate, a better postoperative renal function and reduced ventilation times. Extracorporeal circulation time and postoperative high-dose inotropic support were significantly lower in the MECC group, while the stays in the intensive care unit and in hospital were comparable between the two groups. In our study, age in the ECC group, and previous infarction and New York Heart Association grade IV in the MECC group were preoperative risk factors associated with a higher mortality. Conclusion: Coronary bypass surgery using MECC is feasible and safe for patients with severely impaired left ventricular function. It is a promising alternative to ECC with a low mortality rate and a more favorable postoperative course.

Item Type: Article
Uncontrolled Keywords: CARDIOPULMONARY BYPASS; EJECTION FRACTION; HEART-FAILURE; FOLLOW-UP; ON-PUMP; REVASCULARIZATION; DYSFUNCTION; MANAGEMENT; SURVIVAL; SYSTEM; cardiomyopathy; cardiovascular surgery; coronary bypass surgery
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Anästhesiologie
Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 30 Jul 2020 07:23
Last Modified: 30 Jul 2020 07:23
URI: https://pred.uni-regensburg.de/id/eprint/24700

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