Froelich, K. and Pueschel, R. C. and Birner, M. and Kindermann, J. and Hackenberg, S. and Kleinsasser, N. H. and Hagen, R. and Staudenmaier, R. (2010) Optimization of Fibrinogen Isolation for Manufacturing Autologous Fibrin Glue for Use as Scaffold in Tissue Engineering. ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY, 38 (3). pp. 143-149. ISSN 1073-1199,
Full text not available from this repository. (Request a copy)Abstract
Numerous manufacturing techniques for autogenous fibrin glue used as scaffold material have been described. As there is no consensus regarding the influence of chemical additives on cell biology, it was the aim of this study to establish a method for manufacturing autologous fibrin glue without any additives. The serum part was separated from whole blood. After fibrinogen precipitation, centrifugation was performed to obtain the fibrinogen pellet. Various experimental series were run to examine influences of various temperatures or substituting centrifugation for sedimentation. The method as described here is effective, simple, and performed without any additives, which could potentially influence cell biology.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HUMAN ADIPOSE-TISSUE; IN-VITRO; BONE-MARROW; CARTILAGE; SURGERY; CHONDROCYTES; CELLS; GELS; SEALANTS; ADHESIVE; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Zahnerhaltung und Parodontologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 03 Aug 2020 04:46 |
| Last Modified: | 03 Aug 2020 04:46 |
| URI: | https://pred.uni-regensburg.de/id/eprint/24755 |
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