Symbiotic streptomycetes provide antibiotic combination prophylaxis for wasp offspring

Kroiss, Johannes and Kaltenpoth, Martin and Schneider, Bernd and Schwinger, Maria-Gabriele and Hertweck, Christian and Maddula, Ravi Kumar and Strohm, Erhard and Svatos, Ales (2010) Symbiotic streptomycetes provide antibiotic combination prophylaxis for wasp offspring. NATURE CHEMICAL BIOLOGY, 6 (4). pp. 261-263. ISSN 1552-4450,

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Abstract

Beewolf digger wasps cultivate specific symbiotic bacteria (Streptomyces spp.) that are incorporated into the larval cocoon for protection against pathogens. We identified the molecular basis of this protective symbiosis in the natural context and demonstrate that the bacteria produce a 'cocktail' of nine antibiotic substances. The complementary action of all symbiont-produced antibiotics confers a potent antimicrobial defense for the wasp larvae that parallels the 'combination prophylaxis' known from human medicine.

Item Type: Article
Uncontrolled Keywords: PHYSIOLOGICAL ACTIVITIES; PIERICIDIN; BACTERIA; PROTECT; GARDEN; FUNGI; ANTS;
Subjects: 500 Science > 590 Zoological sciences
Divisions: Biology, Preclinical Medicine > Institut für Zoologie > Evolutionary Ecology (Prof. Dr. Erhard Strohm)
Depositing User: Dr. Gernot Deinzer
Date Deposited: 04 Aug 2020 12:05
Last Modified: 04 Aug 2020 12:05
URI: https://pred.uni-regensburg.de/id/eprint/24936

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