Ditopic crown ether-guanidinium ion receptors for the molecular recognition of amino acids and small peptides

Spaeth, Andreas and Koenig, Burkhard (2010) Ditopic crown ether-guanidinium ion receptors for the molecular recognition of amino acids and small peptides. TETRAHEDRON, 66 (10). pp. 1859-1873. ISSN 0040-4020,

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Abstract

A series of ditopic synthetic receptors based on a crown ether-guanidinium ion recognition motif is reported. The compounds show binding affinity to selected amino acids, including important neuro-transmitters. The effect of the distance of the ammonium and the carboxylate ion, the rigidity of the spacer, and the use of pre-organized pyrrole- and pyrene-guanidinium groups on binding affinity and selectivity are discussed. (C) 2010 Elsevier Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: ABIOTIC GUANIDINIUM; PHASE-TRANSFER; BINDING; REAGENTS; DESIGN; COMPLEXATION; CHEMISTRY; METHANOL; ANIONS; HOST;
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Depositing User: Dr. Gernot Deinzer
Date Deposited: 03 Aug 2020 11:21
Last Modified: 03 Aug 2020 11:21
URI: https://pred.uni-regensburg.de/id/eprint/24980

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