VEGF: A Surrogate Marker for Peripheral Vascular Disease

Stehr, A. and Toepel, I. and Mueller, S. and Unverdorben, K. and Geissler, E. K. and Kasprzak, P. M. and Schlitt, H. J. and Steinbauer, Markus (2010) VEGF: A Surrogate Marker for Peripheral Vascular Disease. EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 39 (3). pp. 330-332. ISSN 1078-5884, 1532-2165

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Abstract

This study aims to evaluate the value of VEGF as a surrogate marker for peripheral vascular disease (PVD). Prior to treatment, serum VEGF levels were evaluated by enzyme-linked immunosorbent assay (ELISA) in 293 PVD patients. Risk factors and clinical parameters of PVD were documented. Twenty-six age-matched healthy volunteers served as controls. Serum VEGF values strongly correlated with Fontaine stages (p < 0.006, stage IV vs. controls). High VEGF values prior to treatment were associated with poor outcome. Serum VEGF appears to indicate the severity of PVD and might serve as a surrogate indicator of disease severity. (C) 2009 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: ENDOTHELIAL GROWTH-FACTOR; Surrogate marker; Peripheral vascular disease; Angiogenesis; Arteriogenesis
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 05 Aug 2020 06:05
Last Modified: 05 Aug 2020 06:05
URI: https://pred.uni-regensburg.de/id/eprint/25065

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