Ott, Ingo and Kowalski, Konrad and Gust, Ronald and Maurer, Joerg and Muecke, Philipp and Winter, Rainer F. (2010) Comparative biological evaluation of two ethylene linked mixed binuclear ferrocene/ruthenium organometallic species. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 20 (3). pp. 866-869. ISSN 0960-894X,
Full text not available from this repository. (Request a copy)Abstract
Two ethylene linked binuclear mixed ferrocene/ruthenium complexes were biologically investigated in comparison to structurally related mononuclear ferrocene or ruthenium species with styryl substituents or ligands. Results indicated that the electron distribution (but not the redox potential), cellular uptake and (to some minor extent) anti-estrogenic effects were the key contributors to antiproliferative effects observed in tumor cell lines. (C) 2010 Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ARENE-RUTHENIUM COMPLEXES; BREAST-CANCER; METAL-COMPLEXES; CELLULAR UPTAKE; FERROCENE; CYTOTOXICITY; DERIVATIVES; SERIES; MODE; Bioorganometallic chemistry; Ferrocene; Ruthenium; Antitumor agents |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Anorganische Chemie > Alumni or Retired Professors > Arbeitskreis Prof. Dr. Rainer Winter |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 07 Aug 2020 09:32 |
| Last Modified: | 07 Aug 2020 09:32 |
| URI: | https://pred.uni-regensburg.de/id/eprint/25176 |
Actions (login required)
 |
View Item |
