Two modifications in the treatment of keratocystic odontogenic tumors (KCOT) and the use of Carnoy's solution (CS)-a retrospective study lasting between 2 and 10 years

Gosau, Martin and Draenert, Florian G. and Mueller, Steffen and Frerich, Bernhard and Buergers, Ralf and Reichert, Thorsten E. and Driemel, Oliver (2010) Two modifications in the treatment of keratocystic odontogenic tumors (KCOT) and the use of Carnoy's solution (CS)-a retrospective study lasting between 2 and 10 years. CLINICAL ORAL INVESTIGATIONS, 14 (1). pp. 27-34. ISSN 1432-6981, 1436-3771

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Abstract

This retrospective study aimed at evaluating the recurrence rates of keratocystic odontogenic tumors (KCOTs) that were enucleated with and without the application of Carnoy's solution (CS). The study included 36 KCOTs treated between 1996 and 2006. Recurrence rates were investigated in correlation with the respective treatment method applied. Additionally, any damage to the inferior alveolar nerve associated with treatment was analyzed. Treatments consisted of enucleation with (38.9%) or without (61.1%) the application of CS. Median follow-up was 4.5 years. Single enucleation showed a recurrence rate of 50%, but the additional application of CS reduced the recurrence rate to 14.3%. No detrimental effects of CS on the mandibular nerve were detected. Enucleation plus the application of CS reduced the recurrence rate of KCOTs compared with simple enucleation. The application of CS did not cause any damage to the mandibular nerve.

Item Type: Article
Uncontrolled Keywords: TERM-FOLLOW-UP; CELL CARCINOMA SYNDROME; SURGICAL-MANAGEMENT; GORLIN-SYNDROME; MARSUPIALIZATION; ENUCLEATION; RECURRENCE; MUTATIONS; PROTOCOL; GENE; KCOT; Carnoy's solution; Enucleation; Keratocyst; Mandibular nerve
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 07 Aug 2020 11:38
Last Modified: 07 Aug 2020 11:38
URI: https://pred.uni-regensburg.de/id/eprint/25186

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