Adjuvant Endocrine Therapy for Breast Cancer During Perimenopause

Noss, D. and Buchholz, S. and Ortmann, O. (2010) Adjuvant Endocrine Therapy for Breast Cancer During Perimenopause. GEBURTSHILFE UND FRAUENHEILKUNDE, 70 (2). pp. 112-116. ISSN 0016-5751

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Abstract

Adjuvant endocrine treatment plays an important role in the treatment of estrogen responsive breast cancer. The treatment options for premenopausal women differ from those for postmenopausal women. Aromatase inhibitors (AI) improve the outcomes in postmenopausal women, while AI can induce an increase in estrogen secretion and tumor growth in premenopausal women. The standard therapy during premenopause remains tamoxifen with or without ovarian suppression by GnRH analogues. Treatment of perimenopausal breast cancer patients can be more complicated, because it is often difficult to determine menopausal status.

Item Type: Article
Uncontrolled Keywords: PREMENOPAUSAL WOMEN; AROMATASE INHIBITORS; RANDOMIZED-TRIALS; HORMONE; TAMOXIFEN; CHEMOTHERAPY; METAANALYSIS; TRANSITION; PROJECT; perimenopause; breast cancer; endocrine therapy; menopausal status
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde)
Depositing User: Petra Gürster
Date Deposited: 09 Apr 2020 10:37
Last Modified: 09 Apr 2020 10:37
URI: https://pred.uni-regensburg.de/id/eprint/25209

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