Mader, Heike S. and Link, Martin and Achatz, Daniela E. and Uhlmann, Katrin and Li, Xiaohua and Wolfbeis, Otto S. (2010) Surface-Modified Upconverting Microparticles and Nanoparticles for Use in Click Chemistries. CHEMISTRY-A EUROPEAN JOURNAL, 16 (18). pp. 5416-5424. ISSN 0947-6539, 1521-3765
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A method is described for modifying the surface of upconverting microparticles (UC mu Ps) and nanoparticles (UCNPs) such that they become amenable to click chemistry. Respective reagents are presented and used in both kinds of particles, either directly or in combination with tetraethoxysilane. The particles also were labeled by using the click reaction, a) with fluorophores to yield materials that have emission colors that depend on the wavelength of excitation; b) with maleinimido groups (so to obtain labels for thiols), and c) with biotin (to make them useful for affinity studies based on the biotin streptavidin system). We believe that both the UC mu Ps and UCNPs have the potential of being used in numerous areas including up-conversion imaging, biolabeling, and derivatization, but also in encoding and security.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | UP-CONVERSION FLUORESCENCE; SILICA NANOPARTICLES; GOLD NANOPARTICLES; CELLS; SIZE; NANOCOMPOSITES; ARCHITECTURES; LIGATION; PHASE; AZIDE; biotin; click chemistry; fluorescence; nanoparticles; upconversion |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Antje J. Bäumner, formerly Prof. Wolfbeis) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 12 Aug 2020 10:27 |
| Last Modified: | 12 Aug 2020 10:27 |
| URI: | https://pred.uni-regensburg.de/id/eprint/25396 |
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