Wenzel, Sabrina M. and Welzel, Julia and Hafner, Christian and Landthaler, Michael and Baeumler, Wolfgang (2010) Permanent make-up colorants may cause severe skin reactions. CONTACT DERMATITIS, 63 (4). pp. 223-227. ISSN 0105-1873, 1600-0536
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Objectives: To investigate severe adverse reactions, such as swelling, burning, and the development of papules, of the lips and the surrounding area in 4 patients who had had at least two PMU procedures on their lips. Patients, Materials and Methods: Adverse skin reactions were examined with patch and prick testing of the colorants. In addition, skin biopsies were taken in the centre of the prick test for histology. One patient declined prick testing. Results: Beauticians tended to use various PMU products, but all contained Pigment Red 181 (CI 73360). All patients tested showed a clear delayed reaction to Pigment Red 181 or the tattoo ink, or both, after prick testing. Histology indicated an allergic reaction. Each lip lesion slowly abated after several months of topical or systemic therapy with steroids in combination with tacrolimus, but none has yet completely resolved. Conclusions: In light of the severe and often therapy-resistant skin reactions, we strongly recommend the regulation and control of the substances used in PMU colorants.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TATTOO; PIGMENTS; COMPLICATIONS; adverse reaction; cosmetic tattooing; CI 73360; CAS no; 2379-74-0; permanent make-up; prick testing |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 17 Aug 2020 06:06 |
| Last Modified: | 17 Aug 2020 06:06 |
| URI: | https://pred.uni-regensburg.de/id/eprint/25419 |
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