Linear IgA disease with ocular involvement associated with ulcerative colitis

Klein, Annette and Wenzel, S. M. and Messmer, E. M. and Landthaler, M. and Vogt, T. (2010) Linear IgA disease with ocular involvement associated with ulcerative colitis. HAUTARZT, 61 (1). pp. 55-57. ISSN 0017-8470,

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Abstract

The association of linear IgA disease (LAD), ulcerative colitis and scarring ocular involvement is very rare and represents a considerable therapeutic challenge. We report a 48-year-old male diagnosed with ulcerative colitis in 1995, who received long-term methylprednisolone therapy. Later, he developed ocular inflammation with conjunctival scarring and synechiae formation as well as episodes of vesicles. Although azathioprine was added to his regimen, the disease was not controlled. After the diagnosis of LAD was established, dapsone was added. With this therapy, the ocular inflammation decreased significantly and the methylprednisolone dose could be successfully tapered slowly without reappearance of vesicles.

Item Type: Article
Uncontrolled Keywords: ; Linear IgA disease; Ulcerative colitis; Cicatrizing conjunctivitis; Autoimmune disorder; Dapsoneoder
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 17 Aug 2020 08:28
Last Modified: 17 Aug 2020 08:28
URI: https://pred.uni-regensburg.de/id/eprint/25467

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