Long-term follow-up of male patients after reconstruction of the bladder-exstrophy-epispadias complex: Psychosocial status, continence, renal and genital function

Ebert, Anne K. and Schott, Guenter and Bals-Pratsch, Monika and Seifert, Bernd and Roesch, Wolfgang H. (2010) Long-term follow-up of male patients after reconstruction of the bladder-exstrophy-epispadias complex: Psychosocial status, continence, renal and genital function. JOURNAL OF PEDIATRIC UROLOGY, 6 (1). pp. 6-10. ISSN 1477-5131,

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Abstract

Objective: There is a paucity of knowledge about long-term outcome issues in the bladder-exstrophy-epispadias complex (BEEC). Adult male BEEC patients were investigated in respect of bladder and renal function, fertility, genital function and psychosocial facts. Patients and methods: In a cross-sectional study, 17 adult male BEEC patients (mean age 23.4 years) from a single centre were evaluated with a questionnaire, renal and bladder ultrasound, blood tests, hormonal profile and semen analysis. Results: Phenotypically one patient had complete epispadias and 16 had classical bladder exstrophy. Five patients underwent a one-stage functional reconstruction as a primary and 12 as a redo procedure. After a mean follow-up of 19.4 years, 15 bladders were preserved with 12 voiding per urethram and 3 performing intermittent catheterization; 2 were secondarily diverted. Significant residual urine was present in 10; kidneys were normal in 14 patients. Sixteen patients proved ejaculations, 3 had normospermia, 7 oligoasthenospermia and 6 azospermia. In patients with only one single bladder neck procedure normospermia was statistically significant. Conclusion: After functional BEEC reconstruction, long-term bladder function is preserved with mostly normal renal function. The number of bladder neck attempts has a significant influence on andrologic outcome. Detailed analysis may detect multifactorial pathogenesis from the impaired sperm quality in the BEEC. (C) 2009 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: NECK RECONSTRUCTION; INCONTINENCE; EXPERIENCE; REPAIR; BOYS; BORN; Long-term follow-up; Bladder-Exstrophy-Epispadias complex; Functional reconstruction; Andrological outcome; Genital function; Psychosocial outcome
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Urologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 20 Aug 2020 12:15
Last Modified: 20 Aug 2020 12:15
URI: https://pred.uni-regensburg.de/id/eprint/25521

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