Current Strategies in Cardiovascular Biomaterial Functionalization

Schopka, Simon and Schmid, Thomas and Schmid, Christof and Lehle, Karla (2010) Current Strategies in Cardiovascular Biomaterial Functionalization. MATERIALS, 3 (1). pp. 638-655. ISSN 1996-1944

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Abstract

Prevention of the coagulation cascade and platelet activation is the foremost demand for biomaterials in contact with blood. In this review we describe the underlying mechanisms of these processes and offer the current state of antithrombotic strategies. We give an overview of methods to prevent protein and platelet adhesion, as well as techniques to immobilize biochemically active molecules on biomaterial surfaces. Finally, recent strategies in biofunctionalization by endothelial cell seeding as well as their possible clinical applications are discussed.

Item Type: Article
Uncontrolled Keywords: ENDOTHELIAL PROGENITOR CELLS; IN-VITRO HEMOCOMPATIBILITY; STAINLESS-STEEL STENT; PROTEIN ADSORPTION; VASCULAR GRAFTS; HUMAN THROMBOMODULIN; ADSORBED FIBRINOGEN; PLATELET-ADHESION; CARDIOPULMONARY BYPASS; ARTIFICIAL SURFACES; tissue engineering; cardiovascular; biomaterials; biofunctionalization
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Depositing User: Petra Gürster
Date Deposited: 08 Apr 2020 05:37
Last Modified: 08 Apr 2020 05:37
URI: https://pred.uni-regensburg.de/id/eprint/25533

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