Koehler, Ulrich and Hildebrandt, Olaf and Fischer, Patrick and Gross, Volker and Sohrabi, Keywan and Timmesfeld, Nina and Peter, Saskia and Urban, Christof and Steiss, Jens-Oliver and Koelsch, Stephan and Kerzel, Sebastian and Weissflog, Andreas (2019) Time course of nocturnal cough and wheezing in children with acute bronchitis monitored by lung sound analysis. EUROPEAN JOURNAL OF PEDIATRICS, 178 (9). pp. 1385-1394. ISSN 0340-6199, 1432-1076
Full text not available from this repository. (Request a copy)Abstract
Cough and wheezing are the predominant symptoms of acute bronchitis. Hitherto, the evaluation of respiratory symptoms was limited to subjective methods such as questionnaires. The main objective of this study was to objectively determine the time course of cough and wheezing in children with acute bronchitis. The impact of nocturnal cough on parent's quality of life was assessed as secondary outcome. In 36 children (2-8 years), the frequency of nocturnal cough and wheezing was recorded during three nights by automated lung sound monitoring. Additionally, parents completed symptom logs, i.e., the Bronchitis Severity Score (BSS), as well as the Parent-proxy Children's Acute Cough-specific Quality of Life Questionnaire (PAC-QoL). During the first night, patients had 34.4 +/- 52.3 (mean +/- SD) cough epochs, which were significantly reduced in night 5 (13.5 +/- 26.5; p < 0.001) and night 9 (12.8 +/- 28.1; p < 0.001). Twenty-two patients had concomitant wheezing, which declined within the observation period as well. All subjective parameters (BSS, Cough log and PAC-QoL) were found to be significantly correlated with the objectively assessed cough parameters. Conclusion: Long-term recording of cough and wheezing offers a useful opportunity to objectively evaluate the time course of respiratory symptoms in children with acute bronchitis. To assess putative effects of pharmacotherapy on nocturnal bronchitis symptoms, future studies in more homogeneous patient groups are needed.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | OF-LIFE QUESTIONNAIRE; COMMON COLD; VALIDATION; SEVERITY; SYMPTOMS; ASTHMA; cough; wheezing; acute bronchitis; acoustic long-term recording; time course |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Kinder- und Jugendmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 31 Mar 2020 07:12 |
| Last Modified: | 31 Mar 2020 07:12 |
| URI: | https://pred.uni-regensburg.de/id/eprint/26378 |
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