Very low birth weight infants as a model to study genetic influences on neonatal weight gain

Spiegler, Juliane and Kattner, Evelyn and Vochem, Matthias and Kuester, Helmuth and Moeller, Jens and Mueller, Dirk and Kribs, Angela and Segerer, Hugo and Wieg, Christian and Nikischin, Werner and von der Wense, Axel and Gebauer, Corinna and Herting, Egbert and Goepel, Wolfgang (2008) Very low birth weight infants as a model to study genetic influences on neonatal weight gain. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 46 (1). pp. 113-116. ISSN 0277-2116,

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Abstract

In a cohort of 829 preterm infants (birth weight below 1500 g) we identified 13 monozygotic, 10 same-sex dizygotic, and 12 same-sex matched singleton pairs. The difference in daily weight gain within pairs was significantly lower in monozygotic twins compared with dizygotic twins or matched singleton pairs. Our data support a strong genetic influence on postnatal growth in preterm infants. Therefore, weight gain of preterm infants may be an interesting model to study polymorphic variants of genes regulating neonatal resorption, metabolism, or energy expenditure, and their influence on weight gain in preterm infants.

Item Type: Article
Uncontrolled Keywords: OBESITY; POLYMORPHISM; OVERWEIGHT; TWINS; RISK; preterm infant; twin study; weight gain
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Kinder- und Jugendmedizin
Depositing User: Dr. Gernot Deinzer
Date Deposited: 18 Nov 2020 09:19
Last Modified: 18 Nov 2020 09:19
URI: https://pred.uni-regensburg.de/id/eprint/31692

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