Subat, Michael and Gallmeier, Hans-Christoph and Fuchs, Andreas and Koenig, Burkhard (2005) Functionalized N-aryl-substituted cyclens by nucleophilic aromatic substitution. SYNTHETIC COMMUNICATIONS, 35 (23). pp. 3003-3019. ISSN 0039-7911,
Full text not available from this repository. (Request a copy)Abstract
The reaction of trifold protected cyclen with fluorinated dinitroarenes yields aryl-substituted or aryl-bridged cyclen derivatives in good yield. The two arene nitro groups, necessary for the nucleophilic aromatic substitution, are subsequently selectively reduced to amines and further functionalized by amide formation. As an example, a cyclen derivative bearing a heterocyclic oligoamide with potential DNA binding ability was prepared.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | COORDINATION; DERIVATIVES; COMPLEXES; AFFINITY; azamacrocycles; DNA binding; ionophore; nucleophilic aromatic substitution |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 21 Jun 2021 07:59 |
| Last Modified: | 21 Jun 2021 07:59 |
| URI: | https://pred.uni-regensburg.de/id/eprint/36832 |
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