Friedrich, Sarah and Raff, Kerstin and Landthaler, Michael and Karrer, Sigrid (2004) Cutaneous ulcerations on hands and heels secondary to long-term hydroxyurea treatment. EUROPEAN JOURNAL OF DERMATOLOGY, 14 (5). pp. 343-346. ISSN 1167-1122, 1952-4013
Full text not available from this repository. (Request a copy)Abstract
Hydroxyurea is a chemotherapeutic agent used to treat myeloproliferative disorders and other non-neoplastic conditions. Cutaneous side-effects have been described in long-term therapy with hydroxyurea and include xerosis, hyperpigmentation, skin atrophy, erythema, alopecia, skin tumours and ulceration of the skin, particularly of the legs. We present a 71-year old patient with chronic myelocytic leukemia (CML) who developed extremely painful ulcers on the hands and heels as well as skin tumours while on long-term therapy with hydroxyurea. The ulcers were resistant to therapy but healed three months after discontinuation of hydroxyurea therapy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SKIN CHANGES SECONDARY; LEG ULCERS; THERAPY; DERMATOMYOSITIS; PSORIASIS; ERUPTION; LEUKEMIA; TUMORS; chronic myelocytic leukemia (CML); cutaneous lesions; skin tumours; hydroxyurea |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 30 Jun 2021 05:17 |
| Last Modified: | 30 Jun 2021 05:17 |
| URI: | https://pred.uni-regensburg.de/id/eprint/37229 |
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