Minuth, Will W. and Strehl, R. and Schumacher, K. (2004) Tissue factory: Conceptual design of a modular system for the in vitro generation of functional tissues. TISSUE ENGINEERING, 10 (1-2). pp. 285-294. ISSN 1076-3279
Full text not available from this repository. (Request a copy)Abstract
Tissue factory is a modular system designed to generate artificial tissues under optimal perfusion culture conditions. The microenvironment within the culture containers can be fine-tuned to meet the physiological needs of individual tissues, so that the generation of differentiated three-dimensional tissue constructs becomes possible. An optimal physiological environment is created by modulating a liquid phase as well as an artificial interstitium surrounding the growing construct. An innovative construction principle allows production of tissue culture containers, gas exchangers, and gas expanders at minimal material expenditure. Therefore it will be possible for the first time to produce sterile one-way perfusion culture modules for the generation of artificial tissues. The modules can be used separately as well as in a combined module. The system is designed to provide a possible platform for the standardized production of artificial tissues for future applications in biomedicine.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BIOARTIFICIAL PANCREAS; ENGINEERED CARTILAGE; COLLAGEN SPONGES; OXYGEN-TENSION; HEART-VALVES; STEM-CELLS; CULTURE; BONE; CHONDROCYTES; SCAFFOLDS; |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Anatomie > Lehrstuhl für Molekulare und zelluläre Anatomie > Prof. Dr. Will Minuth |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 27 Jul 2021 08:53 |
| Last Modified: | 27 Jul 2021 08:53 |
| URI: | https://pred.uni-regensburg.de/id/eprint/38278 |
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