Transcranial magnetic stimulation: New possibilities in characterizing central acting drugs and in phenotyping psychiatric diseases

Eichhammer, P. and Langguth, B. and Kharraz, A. and Wiegand, R. and Hajak, Goeran (2003) Transcranial magnetic stimulation: New possibilities in characterizing central acting drugs and in phenotyping psychiatric diseases. NERVENHEILKUNDE, 22 (7). pp. 354-358. ISSN 0722-1541

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Abstract

Two aspects of transcranial magnetic stimulation (TMS) gain increasing importance in the field of psychiatry. The repetitive transcranial magnetic stimulation (rTMS) as a promising method for treating neuropsychiatric diseases like depression as well as the diagnostic variant of TMS. Methodological improvement of this diagostic variant offer the possibility to measure aspects of cortical excitability painlessly and non-invasively. Using this neurophysiological tool, new insights into the effects of central-acting drugs are possible. Particularly striking seems to be the potential of this approach for use in biological phenotyping. TMS seems to detect neurophysiological endophenotypes that may be the result of genetic variations.

Item Type: Article
Uncontrolled Keywords: MOTOR CORTEX EXCITABILITY; NOREPINEPHRINE-REUPTAKE INHIBITOR; SEROTONIN TRANSPORTER GENE; CORTICAL EXCITABILITY; INTRACORTICAL INHIBITION; PARKINSONS-DISEASE; BRAIN-STIMULATION; SILENT PERIOD; SCHIZOPHRENIA; PROMOTER; transcranial magnetic stimulation; paired-pulse TMS; cortical excitability
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 28 Sep 2021 09:14
Last Modified: 28 Sep 2021 09:14
URI: https://pred.uni-regensburg.de/id/eprint/39508

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