Severe anaphylactic shock without exanthema in a case of unknown latex allergy and review of the literature

Hollnberger, Harald and Gruber, E. and Frank, B. (2002) Severe anaphylactic shock without exanthema in a case of unknown latex allergy and review of the literature. PAEDIATRIC ANAESTHESIA, 12 (6). pp. 544-551. ISSN 1155-5645

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Abstract

We describe a case of severe anaphylactic shock without exanthema in an 8-year-old boy who was undergoing elective surgery for an ileostomy. The boy had a history of four anorectal operations in the newborn period, but no history of allergies. Sudden, profund bronchospasm and cardiorespiratory collapse occurred 30 min after the beginning of the operation. No signs of exanthema or urticaria were seen. The patient was resuscitated successfully and remained ventilated for 25 h. During this time, he needed epinephrine in dosages of 0.3-0.05 mug.kg(-1) .min(-1) . Radioallergosorbent (RAST) tests for the patient were positive Cap Class 3 and 4, and specific immunoglobulin E was highly positive, suggesting a natural rubber latex allergy as the cause of the anaphylactic shock. Ethylene oxide was negative. Eleven days later, a further operation was performed with a strict latex-free protocol in the presence of histamine 1 and 2 receptor antagonists. On this occasion, the intraoperative course was uneventful. Incidence of anaphylactic reactions, prevalence of latex sensitization, special risk groups and management are discussed.

Item Type: Article
Uncontrolled Keywords: NATURAL-RUBBER LATEX; SPINA-BIFIDA; RISK-FACTORS; GENERAL-ANESTHESIA; CHILDREN; HYPERSENSITIVITY; PREVALENCE; SENSITIZATION; MANAGEMENT; MYELODYSPLASIA; natural rubber latex; latex allergy; latex sensitization; complications; anaphylactic shock; children
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Kinder- und Jugendmedizin
Depositing User: Petra Gürster
Date Deposited: 09 Jun 2021 07:06
Last Modified: 09 Jun 2021 07:06
URI: https://pred.uni-regensburg.de/id/eprint/40134

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