Brunner, Henri and Schellerer, Karl-Martin (2002) Double porphyrin platinum conjugates. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 57 (7). pp. 751-756. ISSN 0932-0776
Full text not available from this repository.Abstract
Platinum-containing groups and porphyrins in the same molecule not only show additivity of the dark toxicity of the platinum moiety and the phototoxicity of the porphyrin system but also a selective enrichment of porphyrin platinum conjugates in tumor tissues compared to platinum-only drugs. Porphyrin platinum conjugates containing amino-porphyrin non-leaving groups and porphyrin-carboxylate leaving groups were synthesized and tested with the mammary carcinoma cell line MDA-MB-231.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ANTITUMOR-ACTIVITY; COMPLEXES; LIGANDS; ALCOHOLS; THERAPY; AGENTS; |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Anorganische Chemie > Alumni or Retired Professors > Prof. Dr. Henri Brunner |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 19 Oct 2021 06:03 |
| Last Modified: | 19 Oct 2021 06:03 |
| URI: | https://pred.uni-regensburg.de/id/eprint/40143 |
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