Knoell, Antje and Helmig, Magdalena and Peters, Ove and Jilg, Wolfgang (2001) Hepatitis C virus transmission in a pediatric oncology ward: Analysis of an outbreak and review of the literature. LABORATORY INVESTIGATION, 81 (3). pp. 251-262. ISSN 0023-6837, 1530-0307
Full text not available from this repository. (Request a copy)Abstract
Hospital-related hepatitis C virus (HCV) infections continue to occur even after the introduction of blood donor screening. We report an outbreak of HCV in nine patients of a pediatric oncology ward in 1996/1997. Sequencing of the hypervariable genomic region 1 (HVR1) of the E2/NS1 region showed near identity between HCV isolates from these patients as evidence for infection with the same virus. Despite a detailed and careful investigation, the source of infection and the mode of Virus transmission could not be established. Based on a review of the current literature about nosocomial HCV infection and HCV infection in children, hypotheses for possible means of transmission in this outbreak are discussed.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HEALTH-CARE WORKERS; MOLECULAR EVOLUTIONARY ANALYSIS; CHRONIC-HEMODIALYSIS PATIENTS; NON-B-HEPATITIS; NOSOCOMIAL TRANSMISSION; NEEDLESTICK ACCIDENTS; BLOOD-TRANSFUSION; PHYLOGENETIC ANALYSIS; INTERFERON-ALPHA; RISK-FACTORS; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Kinder- und Jugendmedizin Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene |
| Depositing User: | Petra Gürster |
| Date Deposited: | 07 May 2021 07:53 |
| Last Modified: | 07 May 2021 07:53 |
| URI: | https://pred.uni-regensburg.de/id/eprint/41710 |
Actions (login required)
 |
View Item |
