Treatment Motivations and Expectations in Patients with Actinic Keratosis: A German-Wide Multicenter, Cross-Sectional Trial

Steeb, Theresa and Wessely, Anja and von Bubnoff, Dagmar and Dirschka, Thomas and Drexler, Konstantin and Falkenberg, Conrad and Hassel, Jessica C. and Hayani, Kinan and Huening, Svea and Kaehler, Katharina C. and Karrer, Sigrid and Krammer, Christian and Leiter, Ulrike and Lill, Diana and Marsela, Enklajd and Meiwes, Andreas and Nashan, Dorothee and Nasifoglu, Suzan and Schmitz, Lutz and Sirokay, Judith and Thiem, Alexander and Utikal, Jochen and Zink, Alexander and Berking, Carola and Heppt, Markus V. (2020) Treatment Motivations and Expectations in Patients with Actinic Keratosis: A German-Wide Multicenter, Cross-Sectional Trial. JOURNAL OF CLINICAL MEDICINE, 9 (5): 1438. ISSN , 2077-0383

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Abstract

Patient-centered motives and expectations of the treatment of actinic keratoses (AK) have received little attention until now. Hence, we aimed to profile and cluster treatment motivations and expectations among patients with AK in a nationwide multicenter, cross-sectional study including patients from 14 German skin cancer centers. Patients were asked to complete a self-administered questionnaire. Treatment motives and expectations towards AK management were measured on a visual analogue scale from 1-10. Specific patient profiles were investigated with subgroup and correlation analysis. Overall, 403 patients were included. The highest motivation values were obtained for the items "avoid transition to invasive squamous cell carcinoma" (mean +/- standard deviation; 8.98 +/- 1.46), "AK are considered precancerous lesions" (8.72 +/- 1.34) and "treating physician recommends treatment" (8.10 +/- 2.37; p < 0.0001). The highest expectation values were observed for the items "effective lesion clearance" (8.36 +/- 1.99), "safety" (8.20 +/- 2.03) and "treatment-related costs are covered by health insurance" (8.00 +/- 2.41; p < 0.0001). Patients aged >= 77 years and those with >= 7 lesions were identified at high risk of not undergoing any treatment due to intrinsic and extrinsic motivation deficits. Heat mapping of correlation analysis revealed four clusters with distinct motivation and expectation profiles. This study provides a patient-based heuristic tool for a personalized treatment decision in patients with AK.

Item Type: Article
Uncontrolled Keywords: ; skin cancer; patient education; actinic keratosis; cross-sectional study; patient-centered care; patient-reported outcomes; personalized medicine
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 24 Mar 2021 12:06
Last Modified: 24 Mar 2021 12:06
URI: https://pred.uni-regensburg.de/id/eprint/44632

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