Humberg, Alexander and Haertel, Christoph and Rausch, Tanja K. and Stichtenoth, Guido and Jung, Philipp and Wieg, Christian and Kribs, Angela and von der Wense, Axel and Weller, Ursula and Hoehn, Thomas and Olbertz, Dirk M. and Felderhoff-Mueser, Ursula and Rossi, Rainer and Teig, Norbert and Heitmann, Friedhelm and Schmidtke, Susanne and Bohnhorst, Bettina and Vochem, Matthias and Segerer, Hugo and Moeller, Jens and Eichhorn, Joachim G. and Wintgens, Juergen and Boettger, Ralf and Hubert, Mechthild and Doerdelmann, Michael and Hillebrand, Georg and Roll, Claudia and Jensen, Reinhard and Zemlin, Michael and Moegel, Michael and Werner, Claudius and Schaefer, Stefan and Schaible, Thomas and Franz, Axel and Heldmann, Michael and Ehlers, Silke and Kannt, Olaf and Orlikowsky, Thorsten and Gerleve, Hubert and Schneider, Katja and Haase, Roland and Boeckenholt, Kai and Linnemann, Knud and Herting, Egbert and Goepel, Wolfgang (2020) Active perinatal care of preterm infants in the German Neonatal Network. ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 105 (2). F190-F195. ISSN 1359-2998, 1468-2052
Full text not available from this repository. (Request a copy)Abstract
Objective To determine if survival rates of preterm infants receiving active perinatal care improve over time. Design The German Neonatal Network is a cohort study of preterm infants with birth weight <1500 g. All eligible infants receiving active perinatal care are registered. We analysed data of patients discharged between 2011 and 2016. Setting 43 German level III neonatal intensive care units (NICUs). Patients 8222 preterm infants with a gestational age between 22/0 and 28/6 weeks who received active perinatal care. Interventions Participating NICUs were grouped according to their specific survival rate from 2011 to 2013 to high (percentile >P75), intermediate (P25-P75) and low (<P25) survival. We compared these survival rates with data in 2014-2016. Main outcome measures Death by any cause before discharge. Results Total survival increased from 85.8% in 2011-2013 to 87.4% in 2014-2016. This increase was due to reduced mortality of NICUs with low survival rates in 2011-2013. Survival increased in these centres from 53% to 64% in the 22-24 weeks strata and from 73% to 84% in the 25-26 weeks strata. Conclusions Our data support previous reports that active perinatal care of very immature infants improves outcomes at the border of viability and survival rates at higher gestational ages. The high total number of surviving infants below 24 weeks of gestation challenges national recommendations exclusively referring to gestational age as the single criterion for providing active care. However, more data are needed before recommendations for parental counselling should be reconsidered.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | WEEKS GESTATION; SURVIVAL; OUTCOMES; BORN; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Kinder- und Jugendmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 29 Mar 2021 09:56 |
| Last Modified: | 29 Mar 2021 09:56 |
| URI: | https://pred.uni-regensburg.de/id/eprint/44978 |
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