Weber, Lena and Blachutzik, Oliver and Vielsmeier, Veronika and Andorfer, Kornelia and Matthias, Christoph and Kuenzel, Julian (2021) Evaluation of oesophagoscopy for staging and restaging of head and neck squamous cell carcinoma. LARYNGO-RHINO-OTOLOGIE, 100 (02). pp. 111-119. ISSN 0935-8943, 1438-8685
Full text not available from this repository. (Request a copy)Abstract
Objective Oesophagoscopy is important in diagnostic and follow up investigation in patients with head and neck squamous cell carcinoma (HNSCC). Second primary malignancies of the oesophagus have major impact on therapy of the primary tumour. Considering the low incidence of oesophageal second primaries and the serious complication of oesophageal perforation routine oesophagoscopy is being discussed. Material and Methods Incidence of oesophageal second primaries and complication rates in oesophagoscopy were identified in a systematic review. A retrospective analysis was performed in our own patient collective. To evaluate the current practice at German ENT Clinics a survey was conducted. Results 1053 oesophagoscopies in 800 patients were analysed. In 800 patients seven (0.9%) synchronous secondary malignancies of the oesophagus occurred. In 253 follow up oesophagoscopies five (2 %) metachronous secondary malignancies were discovered. 14 (1.3 %) complications were detected; oesophageal perforation was only detected in one case (0.1 %). There was no association of certain risk factors with the incidence of secondary malignancies. The review of literature showed an incidence of secondary malignancies for Europe/USA of 1.8% and for Asia of 4.1 %. Incidence of oesophageal perforation was 0-0.2%. Survey results showed routine oesophagoscopy in staging (100%) and regularly in follow up (65.3 %). Conclusions Oesophagoscopy is a convenient method to detect secondary malignancies of the oesophagus. To allow a selection of patients developing secondary malignancies according to risk profiles further prospective multicentre studies are required.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; panendoscopy; secondary primary; staging; head and neck cancer; oesophagoscopy |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 06 Sep 2022 06:34 |
| Last Modified: | 06 Sep 2022 06:34 |
| URI: | https://pred.uni-regensburg.de/id/eprint/46630 |
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