Nicolay, U. and Girgsdies, O. E. and Banzhoff, A. and Hundt, E. and Jilg, Wolfgang (1999) Diphtheria booster vaccination: one or two injections? VACCINE, 17 (18). pp. 2223-2228. ISSN 0264-410X,
Full text not available from this repository.Abstract
In a prospective, controlled, randomized, multicenter study the immunogenicity and tolerance of a single vaccination (day 0) and two (day 0, 28) booster vaccinations against diphtheria were compared in subjects who had received their last diphtheria vaccination more than 10 years ago. 415 subjects received the first booster vaccination, and 203 were vaccinated twice. The geometric mean diphtheria antitoxin concentration after the first booster (day 28) was 2.354 I.U./ml, and after the second booster (day 56) 2.238 I.U./ml. Prior to the first vaccination 48.9% of the subjects had a diphtheria antitoxin level below 0.1 I.U./m; after the first and second boosters 95.4% and 97.5% of subjects, respectively, showed a level of at least 0.1 I.U./ml. A clear serological effect of a second booster 4 weeks after the first one could not be demonstrated. (C) 1999 Elsevier Science Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | IMMUNITY; ADULTS; BERLIN; diphtheria; booster; vaccination |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 19 Oct 2022 09:04 |
| Last Modified: | 19 Oct 2022 09:04 |
| URI: | https://pred.uni-regensburg.de/id/eprint/48249 |
Actions (login required)
 |
View Item |
