Listeria monocytogenes-induced endogenous endophthalmitis in an otherwise healthy individual: rapid PCR-diagnosis as the basis for effective treatment

Lohmann, Chris P. and Gabel, V. P. and Heep, M. and Linde, H. J. and Reischl, Udo (1999) Listeria monocytogenes-induced endogenous endophthalmitis in an otherwise healthy individual: rapid PCR-diagnosis as the basis for effective treatment. EUROPEAN JOURNAL OF OPHTHALMOLOGY, 9 (1). pp. 53-57. ISSN 1120-6721,

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Abstract

Purpose. Listeria monocytogenes is a rare cause of endogenous endophthalmitis. To date 15 cases ha ve been published in the literature. All eyes showed similar clinical features and profound visual loss mainly due to delayed diagnosis. Methods. An additional case of an otherwise healthy 73 year-old male, who was referred to our hospital because of acute iridocyclitis with secondary glaucoma, is reported. Within a few days the severity of the intraocular infection increased dramatically, resulting in the clinical picture of acute endophthalmitis. Results. In contrast to most published cases, early identification of the causative pathogen in the aqueous humor after anterior chamber puncture using polymerase chain reaction (PCR) and the initiation of a specific, systemic antibiotic medication, resulted in complete recovery of visual acuity. Conclusions. PCR is very useful for the identification of the pathogen in intraocular infections.

Item Type: Article
Uncontrolled Keywords: CHAIN-REACTION PCR; INFECTIONS; PROBES; endophthalmitis; Listeria monocytogenes; PCR
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Augenheilkunde
Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Depositing User: Dr. Gernot Deinzer
Date Deposited: 29 Nov 2022 13:17
Last Modified: 29 Nov 2022 13:17
URI: https://pred.uni-regensburg.de/id/eprint/48646

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