Faller, Gerhard and Winter, Matthias and Steininger, Helmuth and Lehn, Norbert and Meining, Alexander and Bayerdoerffer, Ekkehard and Kirchner, Thomas (1999) Decrease of antigastric autoantibodies in Helicobacter pylori gastritis after cure of infection. PATHOLOGY RESEARCH AND PRACTICE, 195 (4). pp. 243-246. ISSN 0344-0338,
Full text not available from this repository. (Request a copy)Abstract
H. pylori infection leads to the formation of autoantibodies against canalicular structures within human parietal cells in about 30% of all patients. This type of autoreactivity is associated with gastric mucosa atrophy. This study aimed to analyse the effect of cure of infection on anticanalicular autoantibodies. H. pylovi infection was cured in 34 patients. Sera of these patients were screened for anticanalicular autoantibodies using an immunohistochemical method before, 10 weeks after and one year after cure of infection. Prevalence of anticanalicular autoantibodies significantly decreased from 26% before treatment to 9% after one year. The data presented in this study add new information to the possible reversibility of gastric mucosa atrophy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ATROPHIC BODY GASTRITIS; ERADICATION; MUCOSA; ULCER; H. pylori gastritis; antigastric autoantibodies; eradication therapy; gastric atrophy |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Dec 2022 08:26 |
| Last Modified: | 05 Dec 2022 08:26 |
| URI: | https://pred.uni-regensburg.de/id/eprint/48714 |
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