Heep, Markus and Beck, Daniela and Bayerdoerffer, Ekkehard and Lehn, Norbert (1999) Rifampin and rifabutin resistance mechanism in Helicobacter pylori. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 43 (6). pp. 1497-1499. ISSN 0066-4804,
Full text not available from this repository.Abstract
Eighty-one clinical isolates of Helicobacter pylori showed no resistance to rifampin (MIC range, 0.032 to 2 mu g/ml; MIC at which 50% of isolates are inhibited [MIC50], 0.25 mu g/ml). The MIC50 of rifabutin was 0.008 mu g/ml (n = 16). Alt resistant laboratory mutants of H. pylori ATCC 43504 showed amino acid exchanges in codons 524 to 545 or codon 585 of the rpoB gene, corresponding to the gene sequences from Mycobacterium tuberculosis and Escherichia coli.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MYCOBACTERIUM-TUBERCULOSIS; NEISSERIA-MENINGITIDIS; RNA-POLYMERASE; RPOB MUTATIONS; MUTANTS; STRAINS; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 07 Feb 2023 14:24 |
| Last Modified: | 07 Feb 2023 14:24 |
| URI: | https://pred.uni-regensburg.de/id/eprint/49180 |
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