Hohenleutner, Ulrich and Walther, Thomas and Wenig, Matthias and Baeumler, Wolfgang and Landthaler, Michael (1998) Leg telangiectasia treatment with a 1.5 ms pulsed dye laser, ice cube cooling of the skin and 595 vs 600 nm: Preliminary results. LASERS IN SURGERY AND MEDICINE, 23 (2). pp. 72-78. ISSN 0196-8092,
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Background and Objective: Preliminary results indicate that pulsed dye lasers (PDL) with 1.5 ms pulsewidth and 595 nm wavelength are effective in the treatment of leg telangiectasia. The aim of this study was to evaluate if the clinical results could be improved by a) an effective skin cooling with ice cubes and b) the longer wavelength of 600 nm. Study Desgn/Materials and Methods: In 87 patients with vessels up to 1 mm in diameter, 257 single test treatments were performed using wavelengths of 595 and 600 nm, fluences of 16, 18, and 20 J/cm(2), a 1.5 ms pulse duration, and an elliptical spot of 2 x 7 mm. In 7 patients, the skin surface temperature curve was measured after cooling with ice cubes vs hydrogel dressings, and spot geometry and fluence were investigated with and with out the gel dressing. Results: Vessel clearance was evaluated 6-8 weeks after treatment. 20 J/cm(2) were most effective (80% clearance >50%), and 18 J/cm(2) were more effective than 16 J/cm(2) (66.2 vs 52.5% clearance >50%). There was a tendency towards better results with 595 nm, but the differences were not significant. Vessels with a diameter <0.5 mm cleared significantly better than those with 0.5-1 mm (69.1 vs 31.9% clearance >50%). Hypo- and hyperpigmentation were seen in 32% of the patients. Cooling with ice cubes proved to be far more effective than with hydrogel dressings (temperature decrease approx 15 vs 5 degrees C). Additionally, the gel dressing caused an energy loss of approx 35% and an irregular spot geometry as shown on burn paper. Conclusions: Treatment of leg telangiectasia with the 1.5 ms-PDL is safe and effective, especially in vessels smaller than 0.5 mm in diameter; 595 nm and 18 J/cm(2) seem to be somewhat more effective as 600 nm and 16 J/cm(2); and 20 J/cm(2) are even more effective, but persistent hyperpigmentation cannot yet be excluded due to insufficient follow-up time. Cooling with ice cubes is more effective and less expensive than gel dressings, and the short term clinical results are equivalent, even if the frequency of transient pigmentary changes is increased. (C) 1998 Wiley-Liss, Inc.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SELECTIVE PHOTOTHERMOLYSIS; OPTICS; flashlamp-pumped pulsed dye laser; long pulse dye laser; skin surface temperature; 1.5 ms-pulsewidth |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 31 Oct 2023 10:02 |
| Last Modified: | 31 Oct 2023 10:02 |
| URI: | https://pred.uni-regensburg.de/id/eprint/50254 |
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